Two Distinct Compounds
Despite being frequently studied together, TB-500 and BPC-157 are structurally and mechanistically distinct peptides. Both are available in OzPeptides' Tissue Repair & Recovery research category.
TB-500 (Thymosin Beta-4)
TB-500 refers to the synthetic form of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid protein found in virtually all human and animal cells. It is one of the most abundant intracellular peptides in mammals.
Key research characteristics:
- Actin sequestration — Tβ4 binds G-actin with high affinity, playing a role in cytoskeletal organisation
- Cell migration — Research indicates influence on keratinocyte and endothelial cell migration
- Anti-inflammatory signalling — Tβ4 appears to downregulate inflammatory cytokines in preclinical models
- Molecular weight — ~4963 Da
- Sequence length — 43 amino acids
Our TB-500 10mg is available for research purposes.
BPC-157 (Body Protection Compound-157)
BPC-157 is a 15-amino acid peptide (pentadecapeptide) derived from a protein found in gastric juice. Unlike TB-500, BPC-157 is not naturally occurring in its exact form — it is a synthetic sequence.
Key research characteristics:
- Nitric oxide modulation — Proposed influence on NO synthesis pathways
- Tendon fibroblast activity — Preclinical studies suggest upregulation of GH receptors in tendon cells
- Angiogenesis — VEGF pathway involvement in blood vessel formation during healing
- Molecular weight — ~1419 Da
- Sequence length — 15 amino acids
Structural Comparison
| Property | TB-500 | BPC-157 |
|---|---|---|
| Origin | Natural protein fragment | Synthetic gastric sequence |
| Amino acids | 43 | 15 |
| Molecular weight | ~4963 Da | ~1419 Da |
| Primary research interest | Actin/cell migration | NO/angiogenesis/GH receptor |
| Stability (lyophilised) | Moderate | Good |
Research Approaches
The complementary mechanisms of these two compounds explain why they are frequently studied in parallel. TB-500's larger molecular structure and actin-binding activity operates through different pathways than BPC-157's smaller pentadecapeptide signalling.
Browse our complete Tissue Repair & Recovery category for all available compounds, including both TB-500 and BPC-157 variants.
All products are sold for research and laboratory purposes only. Not intended for human consumption.